Molecular spectrum of KRAS, NRAS, BRAF, PIK3CA, TP53, and APC somatic gene mutations in Arab patients with colorectal cancer: determination of frequency and distribution pattern

BACKGROUND: The frequency rates of mutations such as KRAS, NRAS, BRAF, and PIK3CA in colorectal cancer (CRC) differ among populations. The aim of this study was to assess mutation frequencies in the Arab population and determine their correlations with certain clinicopathological features. METHODS:...

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Detalhes bibliográficos
Publicado no:J Gastrointest Oncol
Main Authors: Al-Shamsi, Humaid O., Jones, Jeremy, Fahmawi, Yazan, Dahbour, Ibrahim, Tabash, Aziz, Abdel-Wahab, Reham, Abousamra, Ahmed O. S., Shaw, Kenna R., Xiao, Lianchun, Hassan, Manal M., Kipp, Benjamin R., Kopetz, Scott, Soliman, Amr S., McWilliams, Robert R., Wolff, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5177568/
https://ncbi.nlm.nih.gov/pubmed/28078112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jgo.2016.11.02
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