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A Novel Missense Mutation of CMT2P Alters Transcription Machinery

OBJECTIVE: Charcot-Marie-Tooth type 2P (CMT2P) has been associated with frame-shift mutations in the RING domain of LRSAM1 (an E3 ligase). This study describes families with a novel missense mutation of LRSAM1 gene and explores pathogenic mechanisms of CMT2P. METHODS: Patients with CMT2P were charac...

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Bibliografische gegevens
Gepubliceerd in:Ann Neurol
Hoofdauteurs: Hu, Bo, Arpag, Sezgi, Zuchner, Stephan, Li, Jun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5177458/
https://ncbi.nlm.nih.gov/pubmed/27615052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24776
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