EhNPC1 and EhNPC2 Proteins Participate in Trafficking of Exogenous Cholesterol in Entamoeba histolytica Trophozoites: Relevance for Phagocytosis

Entamoeba histolytica, the highly phagocytic protozoan causative of human amoebiasis lacks the machinery to synthesize cholesterol. Here, we investigated the presence of NPC1 and NPC2 proteins in this parasite, which are involved in cholesterol trafficking in mammals. Bioinformatics analysis reveale...

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Bibliografiske detaljer
Udgivet i:PLoS Pathog
Main Authors: Bolaños, Jeni, Betanzos, Abigail, Javier-Reyna, Rosario, García- Rivera, Guillermina, Huerta, Miriam, Pais-Morales, Jonnatan, González-Robles, Arturo, Rodríguez, Mario A., Schnoor, Michael, Orozco, Esther
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5176366/
https://ncbi.nlm.nih.gov/pubmed/28002502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006089
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