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EhNPC1 and EhNPC2 Proteins Participate in Trafficking of Exogenous Cholesterol in Entamoeba histolytica Trophozoites: Relevance for Phagocytosis

Entamoeba histolytica, the highly phagocytic protozoan causative of human amoebiasis lacks the machinery to synthesize cholesterol. Here, we investigated the presence of NPC1 and NPC2 proteins in this parasite, which are involved in cholesterol trafficking in mammals. Bioinformatics analysis reveale...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Bolaños, Jeni, Betanzos, Abigail, Javier-Reyna, Rosario, García- Rivera, Guillermina, Huerta, Miriam, Pais-Morales, Jonnatan, González-Robles, Arturo, Rodríguez, Mario A., Schnoor, Michael, Orozco, Esther
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5176366/
https://ncbi.nlm.nih.gov/pubmed/28002502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006089
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