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Entamoeba histolytica EhCP112 Dislocates and Degrades Claudin-1 and Claudin-2 at Tight Junctions of the Intestinal Epithelium

During intestinal invasion, Entamoeba histolytica opens tight junctions (TJs) reflected by transepithelial electrical resistance (TEER) dropping. To explore the molecular mechanisms underlying this, we studied in vitro and in vivo the damage produced by the recombinant E. histolytica cysteine protea...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Cuellar, Patricia, Hernández-Nava, Elizabeth, García-Rivera, Guillermina, Chávez-Munguía, Bibiana, Schnoor, Michael, Betanzos, Abigail, Orozco, Esther
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561765/
https://ncbi.nlm.nih.gov/pubmed/28861400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00372
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