Limited Role for Interleukin-18 in the Host Protection Response to Pulmonary Infection with Pseudomonas aeruginosa in Mice

We report that clearance of Pseudomonas aeruginosa, accumulation of neutrophils, and synthesis of tumor necrosis factor alpha and macrophage inflammatory protein 2 in the infected lung were not largely different in interleukin-18 (IL-18) knockout or transgenic mice compared with control mice. Our re...

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Main Authors: Nakasone, Chikara, Kawakami, Kazuyoshi, Hoshino, Tomoaki, Kawase, Yusuke, Yokota, Koichi, Yoshino, Kohichiro, Takeda, Kiyoshi, Akira, Shizuo, Saito, Atsushi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
Host Response and Inflammation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC517573/
https://ncbi.nlm.nih.gov/pubmed/15385528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.10.6176-6180.2003
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