Myofilament Calcium Sensitivity: Consequences of the Effective Concentration of Troponin I

Control of calcium binding to and dissociation from cardiac troponin C (TnC) is essential to healthy cardiac muscle contraction/relaxation. There are numerous aberrant post-translational modifications and mutations within a plethora of contractile, and even non-contractile, proteins that appear to i...

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Veröffentlicht in:Front Physiol
Hauptverfasser: Siddiqui, Jalal K., Tikunova, Svetlana B., Walton, Shane D., Liu, Bin, Meyer, Meredith, de Tombe, Pieter P., Neilson, Nathan, Kekenes-Huskey, Peter M., Salhi, Hussam E., Janssen, Paul M. L., Biesiadecki, Brandon J., Davis, Jonathan P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Physiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175494/
https://ncbi.nlm.nih.gov/pubmed/28066265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00632
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