S6K2-mediated regulation of TRBP as a determinant of miRNA expression in human primary lymphatic endothelial cells

MicroRNAs (miRNAs) are short non-coding RNAs that silence mRNAs. They are generated following transcription and cleavage by the DROSHA/DGCR8 and DICER/TRBP/PACT complexes. Although it is known that components of the miRNA biogenesis machinery can be phosphorylated, it remains poorly understood how t...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Warner, Matthew J., Bridge, Katherine S., Hewitson, James P., Hodgkinson, Michael R., Heyam, Alex, Massa, Bailey C., Haslam, Jessica C., Chatzifrangkeskou, Maria, Evans, Gareth J.O., Plevin, Michael J., Sharp, Tyson V., Lagos, Dimitris
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
Soggetti:
RNA
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175334/
https://ncbi.nlm.nih.gov/pubmed/27407113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw631
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