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Argonaute Utilization for miRNA Silencing Is Determined by Phosphorylation-Dependent Recruitment of LIM-Domain-Containing Proteins

As core components of the microRNA-induced silencing complex (miRISC), Argonaute (AGO) proteins interact with TNRC6 proteins, recruiting other effectors of translational repression/mRNA destabilization. Here, we show that LIMD1 coordinates the assembly of an AGO-TNRC6 containing miRISC complex by bi...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cell Rep
मुख्य लेखकों: Bridge, Katherine S., Shah, Kunal M., Li, Yigen, Foxler, Daniel E., Wong, Sybil C.K., Miller, Duncan C., Davidson, Kathryn M., Foster, John G., Rose, Ruth, Hodgkinson, Michael R., Ribeiro, Paulo S., Aboobaker, A. Aziz, Yashiro, Kenta, Wang, Xiaozhong, Graves, Paul R., Plevin, Michael J., Lagos, Dimitris, Sharp, Tyson V.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Cell Press 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507773/
https://ncbi.nlm.nih.gov/pubmed/28683311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.06.027
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