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Argonaute Utilization for miRNA Silencing Is Determined by Phosphorylation-Dependent Recruitment of LIM-Domain-Containing Proteins
As core components of the microRNA-induced silencing complex (miRISC), Argonaute (AGO) proteins interact with TNRC6 proteins, recruiting other effectors of translational repression/mRNA destabilization. Here, we show that LIMD1 coordinates the assembly of an AGO-TNRC6 containing miRISC complex by bi...
में बचाया:
| में प्रकाशित: | Cell Rep |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Cell Press
2017
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5507773/ https://ncbi.nlm.nih.gov/pubmed/28683311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.06.027 |
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