S6K2-mediated regulation of TRBP as a determinant of miRNA expression in human primary lymphatic endothelial cells

MicroRNAs (miRNAs) are short non-coding RNAs that silence mRNAs. They are generated following transcription and cleavage by the DROSHA/DGCR8 and DICER/TRBP/PACT complexes. Although it is known that components of the miRNA biogenesis machinery can be phosphorylated, it remains poorly understood how t...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Warner, Matthew J., Bridge, Katherine S., Hewitson, James P., Hodgkinson, Michael R., Heyam, Alex, Massa, Bailey C., Haslam, Jessica C., Chatzifrangkeskou, Maria, Evans, Gareth J.O., Plevin, Michael J., Sharp, Tyson V., Lagos, Dimitris
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
RNA
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175334/
https://ncbi.nlm.nih.gov/pubmed/27407113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw631
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