The Glycan-Rich Outer Layer of the Cell Wall of Mycobacterium tuberculosis Acts as an Antiphagocytic Capsule Limiting the Association of the Bacterium with Macrophages

Mycobacterium tuberculosis, the causative agent of tuberculosis, is a facultative intracellular pathogen that infects macrophages and other host cells. We show that sonication of M. tuberculosis results in the removal of material from the surface capsule-like layer of the bacteria, resulting in an e...

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Detalhes bibliográficos
Main Authors: Stokes, Richard W., Norris-Jones, Raymond, Brooks, Donald E., Beveridge, Terry J., Doxsee, Dan, Thorson, Lisa M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC517526/
https://ncbi.nlm.nih.gov/pubmed/15385466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.10.5676-5686.2004
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