The Glycan-Rich Outer Layer of the Cell Wall of Mycobacterium tuberculosis Acts as an Antiphagocytic Capsule Limiting the Association of the Bacterium with Macrophages

Mycobacterium tuberculosis, the causative agent of tuberculosis, is a facultative intracellular pathogen that infects macrophages and other host cells. We show that sonication of M. tuberculosis results in the removal of material from the surface capsule-like layer of the bacteria, resulting in an e...

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Main Authors: Stokes, Richard W., Norris-Jones, Raymond, Brooks, Donald E., Beveridge, Terry J., Doxsee, Dan, Thorson, Lisa M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC517526/
https://ncbi.nlm.nih.gov/pubmed/15385466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.10.5676-5686.2004
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