The Glycan-Rich Outer Layer of the Cell Wall of Mycobacterium tuberculosis Acts as an Antiphagocytic Capsule Limiting the Association of the Bacterium with Macrophages

Mycobacterium tuberculosis, the causative agent of tuberculosis, is a facultative intracellular pathogen that infects macrophages and other host cells. We show that sonication of M. tuberculosis results in the removal of material from the surface capsule-like layer of the bacteria, resulting in an e...

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Autori principali: Stokes, Richard W., Norris-Jones, Raymond, Brooks, Donald E., Beveridge, Terry J., Doxsee, Dan, Thorson, Lisa M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC517526/
https://ncbi.nlm.nih.gov/pubmed/15385466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.10.5676-5686.2004
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