The Glycan-Rich Outer Layer of the Cell Wall of Mycobacterium tuberculosis Acts as an Antiphagocytic Capsule Limiting the Association of the Bacterium with Macrophages

Mycobacterium tuberculosis, the causative agent of tuberculosis, is a facultative intracellular pathogen that infects macrophages and other host cells. We show that sonication of M. tuberculosis results in the removal of material from the surface capsule-like layer of the bacteria, resulting in an e...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Stokes, Richard W., Norris-Jones, Raymond, Brooks, Donald E., Beveridge, Terry J., Doxsee, Dan, Thorson, Lisa M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2004
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC517526/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15385466/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.10.5676-5686.2004
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