The Glycan-Rich Outer Layer of the Cell Wall of Mycobacterium tuberculosis Acts as an Antiphagocytic Capsule Limiting the Association of the Bacterium with Macrophages

Mycobacterium tuberculosis, the causative agent of tuberculosis, is a facultative intracellular pathogen that infects macrophages and other host cells. We show that sonication of M. tuberculosis results in the removal of material from the surface capsule-like layer of the bacteria, resulting in an e...

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Bibliografische gegevens
Hoofdauteurs: Stokes, Richard W., Norris-Jones, Raymond, Brooks, Donald E., Beveridge, Terry J., Doxsee, Dan, Thorson, Lisa M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2004
Onderwerpen:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC517526/
https://ncbi.nlm.nih.gov/pubmed/15385466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.10.5676-5686.2004
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