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Suppression of NLRP3 Inflammasome Activation Ameliorates Chronic Kidney Disease-Induced Cardiac Fibrosis and Diastolic Dysfunction

Cardiac fibrosis is a common finding in patients with chronic kidney disease. Here, we investigate the cardio-renal effects of theracurmin, a novel formulation of the polyphenolic compound curcumin, in a rat model of chronic kidney disease. Briefly, Sprague-Dawley rats were randomized to undergo sha...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Bugyei-Twum, Antoinette, Abadeh, Armin, Thai, Kerri, Zhang, Yanling, Mitchell, Melissa, Kabir, Golam, Connelly, Kim A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175152/
https://ncbi.nlm.nih.gov/pubmed/28000751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39551
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