Effect of various anticoagulants on the bioanalysis of drugs in rat blood: implication for pharmacokinetic studies of anticancer drugs

BACKGROUND: Pharmacokinetic studies are vital in development and optimization of drugs. While blood samples can be collected either in EDTA, heparin or citrate containing tubes for the estimation of drug levels in plasma, EDTA tubes are more commonly used. The purpose of this study was to evaluate t...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Springerplus
Autori principali: Kulkarni, Preeti, Karanam, Ashwin, Gurjar, Murari, Dhoble, Sagar, Naik, Arvind B., Vidhun, Bhaskar H., Gota, Vikram
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2016
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5174014/
https://ncbi.nlm.nih.gov/pubmed/28053832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-016-3770-4
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