Glucose metabolism and AMPK signaling regulate dopaminergic cell death induced by gene (α-synuclein)-environment (paraquat) interactions

While environmental exposures are not the single cause of Parkinson’s disease (PD), their interaction with genetic alterations is thought to contribute to neuronal dopaminergic degeneration. However, the mechanisms involved in dopaminergic cell death induced by gene-environment interactions remain u...

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Veröffentlicht in:Mol Neurobiol
Hauptverfasser: Anandhan, Annadurai, Lei, Shulei, Levytskyy, Roman, Pappa, Aglaia, Panayiotidis, Mihalis I, Cerny, Ronald L., Oleh, Khalimonchuk, Powers, Robert, Franco, Rodrigo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173445/
https://ncbi.nlm.nih.gov/pubmed/27324791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-016-9906-2
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