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Conserved region C functions to regulate PD-1 expression and subsequent CD8 T cell memory()

Expression of programmed death 1 (PD-1) on CD8 T cells promotes T cell exhaustion during chronic antigen exposure. During acute infections, PD-1 is transiently expressed and has the potential to modulate CD8 T cell memory formation. Conserved Region C (CR-C), a promoter proximal cis-regulatory eleme...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Bally, Alexander P. R., Tang, Yan, Lee, Joshua T., Barwick, Benjamin G., Martinez, Ryan, Evavold, Brian D., Boss, Jeremy M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173413/
https://ncbi.nlm.nih.gov/pubmed/27895178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601464
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