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Genetic and epigenetic regulation of PD-1 expression()

The inhibitory immune receptor Programmed cell death-1 (PD-1) is intricately regulated. In T cells, PD-1 is expressed in response to most immune challenges, but is rapidly down regulated in acute settings, allowing for normal immune responses. On chronically stimulated antigen-specific T cells, PD-1...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Bally, Alexander P.R., Austin, James W., Boss, Jeremy M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780223/
https://ncbi.nlm.nih.gov/pubmed/26945088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502643
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