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Allosteric Pathways in Tetrahydrofolate Sensing Riboswitch with Dynamics Correlation Network

Riboswitches are cis-acting genetic control elements. Due to their fundamental importance in bacteria gene regulation, riboswitches have been proposed as antibacterial drug targets. Tetrahydrofolate (THF) is an essential cofactor of one-carbon transfer reaction and downregulates the expression of do...

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Bibliographic Details
Published in:Mol Biosyst
Main Authors: Zhang, Jin-Mai, Jiang, Cheng, Ye, Wei, Luo, Ray, Chen, Hai-Feng
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173395/
https://ncbi.nlm.nih.gov/pubmed/27841427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6mb00630b
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