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Islet Adaptations in Fetal Sheep Persist Following Chronic Exposure to High Norepinephrine

Complications in pregnancy elevate fetal norepinephrine (NE) concentrations. Previous studies in NE-infused sheep fetuses revealed that sustained exposure to high NE resulted in lower expression of α(2)-adrenergic receptors in islets and increased insulin secretion responsiveness after acutely termi...

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Detalhes bibliográficos
Publicado no:J Endocrinol
Main Authors: Chen, Xiaochuan, Kelly, Amy C., Yates, Dustin T., Macko, Antoni R., Lynch, Ronald M., Limesand, Sean W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173394/
https://ncbi.nlm.nih.gov/pubmed/27888197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-16-0445
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