Hypoxaemia-induced catecholamine secretion from adrenal chromaffin cells inhibits glucose-stimulated hyperinsulinaemia in fetal sheep

Hypoxaemia elicits adrenergic suppression of fetal glucose-stimulated hyperinsulinaemia. We postulate that this effect is mediated by catecholamines, exclusively, from fetal adrenal chromaffin cells. To investigate this hypothesis, square-wave hyperglycaemic clamp studies were performed under normox...

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Detalhes bibliográficos
Main Authors: Yates, Dustin T, Macko, Antoni R, Chen, Xiaochuan, Green, Alice S, Kelly, Amy C, Anderson, Miranda J, Fowden, Abigail L, Limesand, Sean W
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Renal and Endocrine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515829/
https://ncbi.nlm.nih.gov/pubmed/22907052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.237347
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