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Hypoxia regulates TRAIL sensitivity of colorectal cancer cells through mitochondrial autophagy
The capacity of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to selectively induce cell death in malignant cells triggered numerous attempts for therapeutic exploitation. In clinical trials, however, TRAIL did not live up to the expectations, as tumors exhibit high rates of TRAIL...
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| Udgivet i: | Oncotarget |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Impact Journals LLC
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5173074/ https://ncbi.nlm.nih.gov/pubmed/27166192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9206 |
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