RhoE/ROCK2 regulates chemoresistance through NF-κB/IL-6/ STAT3 signaling in hepatocellular carcinoma

Small Rho GTPase (Rho) and its immediate effector Rho kinase (ROCK) are reported to regulate cell survival, but the detailed molecular mechanism remains largely unknown. We had previously shown that Rho/ROCK signaling was highly activated in hepatocellular carcinoma (HCC). In this study, we further...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Ma, Wei, Sze, Karen Man-Fong, Chan, Lo Kong, Lee, Joyce Man-Fong, Wei, Larry Lai, Wong, Chun-Ming, Lee, Terence Kin-Wah, Wong, Carmen Chak-Lui, Ng, Irene Oi-Lin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173071/
https://ncbi.nlm.nih.gov/pubmed/27213590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9441
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