Reprogramming human A375 amelanotic melanoma cells by catalase overexpression: Upregulation of antioxidant genes correlates with regression of melanoma malignancy and with malignant progression when downregulated

Reactive oxygen species (ROS) are implicated in tumor transformation. The antioxidant system (AOS) protects cells from ROS damage. However, it is also hijacked by cancers cells to proliferate within the tumor. Thus, identifying proteins altered by redox imbalance in cancer cells is an attractive pro...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bracalente, Candelaria, Ibañez, Irene L., Berenstein, Ariel, Notcovich, Cintia, Cerda, María B., Klamt, Fabio, Chernomoretz, Ariel, Durán, Hebe
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173049/
https://ncbi.nlm.nih.gov/pubmed/27206673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9273
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