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Phosphorylation and Subcellular Localization of p27Kip1 Regulated by Hydrogen Peroxide Modulation in Cancer Cells

The Cyclin-dependent kinase inhibitor 1B (p27Kip1) is a key protein in the decision between proliferation and cell cycle exit. Quiescent cells show nuclear p27Kip1, but this protein is exported to the cytoplasm in response to proliferating signals. We recently reported that catalase treatment increa...

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Detalhes bibliográficos
Main Authors: Ibañez, Irene L., Bracalente, Candelaria, Notcovich, Cintia, Tropper, Ivanna, Molinari, Beatriz L., Policastro, Lucía L., Durán, Hebe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435274/
https://ncbi.nlm.nih.gov/pubmed/22970236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044502
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