Reprogramming human A375 amelanotic melanoma cells by catalase overexpression: Upregulation of antioxidant genes correlates with regression of melanoma malignancy and with malignant progression when downregulated

Reactive oxygen species (ROS) are implicated in tumor transformation. The antioxidant system (AOS) protects cells from ROS damage. However, it is also hijacked by cancers cells to proliferate within the tumor. Thus, identifying proteins altered by redox imbalance in cancer cells is an attractive pro...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Bracalente, Candelaria, Ibañez, Irene L., Berenstein, Ariel, Notcovich, Cintia, Cerda, María B., Klamt, Fabio, Chernomoretz, Ariel, Durán, Hebe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173049/
https://ncbi.nlm.nih.gov/pubmed/27206673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9273
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