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Prophylactic Total Gastrectomy for Hereditary Diffuse Gastric Cancer

Germline mutations in the CDH1 gene that produces E-cadherin have been implicated in the development of early-onset diffuse gastric cancer, termed hereditary diffuse gastric cancer. The mean age of gastric cancer diagnosis in affected individuals is 37 years. By age 80, CDH1 mutation carriers who fu...

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Detalles Bibliográficos
Publicado en:ACG Case Rep J
Main Authors: Shepard, Benjamin, Yoder, Leon, Holmes, Cynthia
Formato: Artigo
Idioma:Inglês
Publicado: American College of Gastroenterology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171935/
https://ncbi.nlm.nih.gov/pubmed/28008412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14309/crj.2016.152
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