Chromoendoscopic surveillance in hereditary diffuse gastric cancer: an alternative to prophylactic gastrectomy?

Background: Hereditary diffuse gastric cancer (HDGC) is defined by germline mutations in the E-cadherin gene, CDH-1. The first family in which CDH-1 mutations were identified was a large Maori kindred, where lifetime penetrance is 70%. Prophylactic gastrectomy is an unacceptable option for many muta...

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Detalhes bibliográficos
Main Authors: Shaw, D, Blair, V, Framp, A, Harawira, P, McLeod, M, Guilford, P, Parry, S, Charlton, A, Martin, I
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 by Gut 2005
Assuntos:
Gastric Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774455/
https://ncbi.nlm.nih.gov/pubmed/15753528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2004.049171
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