A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice

Asthma has multiple features, including airway hyperreactivity, inflammation and remodelling. The TNF superfamily member TNFSF14 (LIGHT), via interactions with the receptor TNFRSF14 (HVEM), can support T(H)2 cell generation and longevity and promote airway remodelling in mouse models of asthma, but...

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Vydáno v:Nat Commun
Hlavní autoři: Sibilano, Riccardo, Gaudenzio, Nicolas, DeGorter, Marianne K., Reber, Laurent L., Hernandez, Joseph D., Starkl, Philipp M., Zurek, Oliwia W., Tsai, Mindy, Zahner, Sonja, Montgomery, Stephen B., Roers, Axel, Kronenberg, Mitchell, Yu, Mang, Galli, Stephen J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171877/
https://ncbi.nlm.nih.gov/pubmed/27982078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13696
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