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Biliary Phospholipids Sustain Enterocyte Proliferation and Intestinal Tumor Progression via Nuclear Receptor Lrh1 in mice

The proliferative-crypt compartment of the intestinal epithelium is enriched in phospholipids and accumulation of phospholipids has been described in colorectal tumors. Here we hypothesize that biliary phospholipid flow could directly contribute to the proliferative power of normal and dysplastic en...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Petruzzelli, Michele, Piccinin, Elena, Pinto, Claudio, Peres, Claudia, Bellafante, Elena, Moschetta, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171812/
https://ncbi.nlm.nih.gov/pubmed/27995969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39278
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