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Biliary Phospholipids Sustain Enterocyte Proliferation and Intestinal Tumor Progression via Nuclear Receptor Lrh1 in mice

The proliferative-crypt compartment of the intestinal epithelium is enriched in phospholipids and accumulation of phospholipids has been described in colorectal tumors. Here we hypothesize that biliary phospholipid flow could directly contribute to the proliferative power of normal and dysplastic en...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Petruzzelli, Michele, Piccinin, Elena, Pinto, Claudio, Peres, Claudia, Bellafante, Elena, Moschetta, Antonio
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171812/
https://ncbi.nlm.nih.gov/pubmed/27995969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39278
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