The nuclear receptor LRH-1 critically regulates extra-adrenal glucocorticoid synthesis in the intestine

The nuclear receptor liver receptor homologue-1 (LRH-1, NR5A2) is a crucial transcriptional regulator of many metabolic pathways. In addition, LRH-1 is expressed in intestinal crypt cells where it regulates the epithelial cell renewal and contributes to tumorigenesis through the induction of cell cy...

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Hlavní autoři: Mueller, Matthias, Cima, Igor, Noti, Mario, Fuhrer, Andrea, Jakob, Sabine, Dubuquoy, Laurent, Schoonjans, Kristina, Brunner, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2006
Témata:
Brief Definitive Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118403/
https://ncbi.nlm.nih.gov/pubmed/16923850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060357
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