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The nuclear receptor LRH-1 critically regulates extra-adrenal glucocorticoid synthesis in the intestine
The nuclear receptor liver receptor homologue-1 (LRH-1, NR5A2) is a crucial transcriptional regulator of many metabolic pathways. In addition, LRH-1 is expressed in intestinal crypt cells where it regulates the epithelial cell renewal and contributes to tumorigenesis through the induction of cell cy...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118403/ https://ncbi.nlm.nih.gov/pubmed/16923850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060357 |
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