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A systematic mutational analysis of hormone-binding determinants in the human growth hormone receptor.

A mutational strategy is presented that allowed us to identify hormone-binding determinants in the extracellular portion of the human growth hormone receptor (hGHbp), a 238-residue protein with sequence homology to a number of cytokine receptors. By systematically replacing side chains with alanine...

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Detalhes bibliográficos
Main Authors: Bass, S H, Mulkerrin, M G, Wells, J A
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC51688/
https://ncbi.nlm.nih.gov/pubmed/2034689
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