A single arginine residue determines species specificity of the human growth hormone receptor.

Although growth hormone (GH) receptors (GHRs) in many species bind human (h) GH as well as their own GH, the hGHR only binds primate GH. Arg43 in hGHR interacts with Asp171 of hGH. Nonprimates have a His in the position equivalent to residue 171 of primate GH and a Leu in position 43 of primate GHR....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Souza, S C, Frick, G P, Wang, X, Kopchick, J J, Lobo, R B, Goodman, H M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1995
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC42616/
https://ncbi.nlm.nih.gov/pubmed/7862673
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