The Ku Protein Complex Interacts with YY1, Is Up-Regulated in Human Heart Failure, and Represses α Myosin Heavy-Chain Gene Expression

Human heart failure is accompanied by repression of genes such as α myosin heavy chain (αMyHC) and SERCA2A and the induction of fetal genes such as βMyHC and atrial natriuretic factor. It seems likely that changes in MyHC isoforms contribute to the poor contractility seen in heart failure, because s...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Autores principales:	Sucharov, Carmen C., Helmke, Steve M., Langer, Stephen J., Perryman, M. Benjamin, Bristow, Michael, Leinwand, Leslie
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 2004
Materias:	Transcriptional Regulation
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC516749/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15367688/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.19.8705-8715.2004
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