The Ku Protein Complex Interacts with YY1, Is Up-Regulated in Human Heart Failure, and Represses α Myosin Heavy-Chain Gene Expression

Human heart failure is accompanied by repression of genes such as α myosin heavy chain (αMyHC) and SERCA2A and the induction of fetal genes such as βMyHC and atrial natriuretic factor. It seems likely that changes in MyHC isoforms contribute to the poor contractility seen in heart failure, because s...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Sucharov, Carmen C., Helmke, Steve M., Langer, Stephen J., Perryman, M. Benjamin, Bristow, Michael, Leinwand, Leslie
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2004
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC516749/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15367688/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.19.8705-8715.2004
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