The Ku Protein Complex Interacts with YY1, Is Up-Regulated in Human Heart Failure, and Represses α Myosin Heavy-Chain Gene Expression

Human heart failure is accompanied by repression of genes such as α myosin heavy chain (αMyHC) and SERCA2A and the induction of fetal genes such as βMyHC and atrial natriuretic factor. It seems likely that changes in MyHC isoforms contribute to the poor contractility seen in heart failure, because s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Biol
Prif Awduron: Sucharov, Carmen C., Helmke, Steve M., Langer, Stephen J., Perryman, M. Benjamin, Bristow, Michael, Leinwand, Leslie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2004
Pynciau:
Transcriptional Regulation
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC516749/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15367688/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.19.8705-8715.2004
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