The Hinge-Helix 1 Region of Peroxisome Proliferator-Activated Receptor γ1 (PPARγ1) Mediates Interaction with Extracellular Signal-Regulated Kinase 5 and PPARγ1 Transcriptional Activation: Involvement in Flow-Induced PPARγ Activation in Endothelial Cells

Peroxisome proliferator-activated receptors (PPAR) are ligand-activated transcription factors that form a subfamily of the nuclear receptor gene family. Since both flow and PPARγ have atheroprotective effects and extracellular signal-regulated kinase 5 (ERK5) kinase activity is significantly increas...

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Detalhes bibliográficos
Main Authors: Akaike, Masashi, Che, Wenyi, Marmarosh, Nicole-Lerner, Ohta, Shinsuke, Osawa, Masaki, Ding, Bo, Berk, Bradford C., Yan, Chen, Abe, Jun-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC516745/
https://ncbi.nlm.nih.gov/pubmed/15367687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.19.8691-8704.2004
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