Bcr kinase activation by Angiotensin II inhibits PPARγ transcriptional activity in vascular smooth muscle cells

Bcr is a serine/threonine kinase activated by PDGF that is highly expressed in the neointima after vascular injury. Here, we demonstrate that Bcr is an important mediator of angiotensin II (AngII) and PDGF mediated inflammatory responses in vascular smooth muscle cells (VSMC). Among transcription fa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Alexis, Jeffrey D., Wang, Nadan, Che, Wenyi, Lerner-Marmarosh, Nicole, Sahni, Abha, Korshunov, Vyacheslav A., Zou, Yiping, Ding, Bo, Yan, Chen, Berk, Bradford C., Abe, Jun-ichi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642522/
https://ncbi.nlm.nih.gov/pubmed/19023129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.188409
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