Notch4 Signaling Induces a Mesenchymal–Epithelial–like Transition in Melanoma Cells to Suppress Malignant Behaviors

The effects of Notch signaling are context-dependent and both oncogenic and tumor-suppressive functions have been described. Notch signaling in melanoma is considered oncogenic, but clinical trials testing Notch inhibition in this malignancy have not proved successful. Here, we report that expressio...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Rad, Ehsan Bonyadi, Hammerlindl, Heinz, Wels, Christian, Popper, Ulrich, Menon, Dinoop Ravindran, Breiteneder, Heimo, Kitzwoegerer, Melitta, Hafner, Christine, Herlyn, Meenhard, Bergler, Helmut, Schaider, Helmut
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5167360/
https://ncbi.nlm.nih.gov/pubmed/26801977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1722
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