Expression of chondroitin sulfate proteoglycan 4 (CSPG4) in melanoma cells is downregulated upon inhibition of BRAF

Chondroitin sulfate proteoglycan 4 (CSPG4) is a multifunctional transmembrane proteoglycan involved in spreading, migration and invasion of melanoma. In addition to the activating BRAF V600E mutation, CSPG4 was shown to promote MAPK signaling by mediating the growth-factor induced activation of rece...

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Pubblicato in:Oncol Rep
Autori principali: Uranowska, Karolina, Kalic, Tanja, Valtsanidis, Veronika, Kitzwögerer, Melitta, Breiteneder, Heimo, Hafner, Christine
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2021
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876987/
https://ncbi.nlm.nih.gov/pubmed/33649790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2021.7965
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