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Tumor cell-intrinsic phenotypic plasticity facilitates adaptive cellular reprogramming driving acquired drug resistance

The enthusiasm about successful novel therapeutic strategies in cancer is often quickly dampened by the development of drug resistance. This is true for targeted therapies using tyrosine kinase inhibitors for EGFR or BRAF mutant cancers, but is also an increasingly recognized problem for immunothera...

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Bibliografiske detaljer
Udgivet i:J Cell Commun Signal
Main Authors: Hammerlindl, Heinz, Schaider, Helmut
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5842196/
https://ncbi.nlm.nih.gov/pubmed/29192388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-017-0435-1
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