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Mechanism of the intrinsic arginine finger in heterotrimeric G proteins

Heterotrimeric G proteins are crucial molecular switches that maintain a large number of physiological processes in cells. The signal is encoded into surface alterations of the Gα subunit that carries GTP in its active state and GDP in its inactive state. The ability of the Gα subunit to hydrolyze G...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Mann, Daniel, Teuber, Christian, Tennigkeit, Stefan A., Schröter, Grit, Gerwert, Klaus, Kötting, Carsten
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5167181/
https://ncbi.nlm.nih.gov/pubmed/27911799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1612394113
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