TNFα-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury

TNFα-stimulated gene-6 (TSG6), a 30-kDa protein generated by activated macrophages, modulates inflammation; however, its mechanism of action and role in the activation of macrophages are not fully understood. Here we observed markedly augmented LPS-induced inflammatory lung injury and mortality in T...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Mittal, Manish, Tiruppathi, Chinnaswamy, Nepal, Saroj, Zhao, You-Yang, Grzych, Dagmara, Soni, Dheeraj, Prockop, Darwin J., Malik, Asrar B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5167170/
https://ncbi.nlm.nih.gov/pubmed/27911817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614935113
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