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Ultrasound-mediated Drug Delivery to the Brain: Principles, Progress and Prospects

The blood-brain barrier (BBB) limits drug delivery to the central nervous system. When combined with microbubbles, ultrasound can transiently permeate blood vessels in the brain. This approach, which can be referred to as sonoporation or sonopermeabilization, holds significant promise for shuttling...

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Bibliographic Details
Published in:Drug Discov Today Technol
Main Authors: Dasgupta, Anshuman, Liu, Mengjiao, Ojha, Tarun, Storm, Gert, Kiessling, Fabian, Lammers, Twan
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5166975/
https://ncbi.nlm.nih.gov/pubmed/27986222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ddtec.2016.07.007
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