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Multidrug Resistance: Physiological Principles and Nanomedical Solutions
Multidrug (MDR) resistance is a pathophysiological phenomenon employed by cancer cells which limits the prolonged and effective use of chemotherapeutic agents. MDR is primarily based on the over-expression of drug efflux pumps in the cellular membrane. Prominent examples of such efflux pumps, which...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3939439/ https://ncbi.nlm.nih.gov/pubmed/24120954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2013.09.018 |
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