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Ultrasound-mediated Drug Delivery to the Brain: Principles, Progress and Prospects

The blood-brain barrier (BBB) limits drug delivery to the central nervous system. When combined with microbubbles, ultrasound can transiently permeate blood vessels in the brain. This approach, which can be referred to as sonoporation or sonopermeabilization, holds significant promise for shuttling...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Drug Discov Today Technol
Hauptverfasser: Dasgupta, Anshuman, Liu, Mengjiao, Ojha, Tarun, Storm, Gert, Kiessling, Fabian, Lammers, Twan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5166975/
https://ncbi.nlm.nih.gov/pubmed/27986222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ddtec.2016.07.007
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