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Atg8 family LC3/GABARAP proteins are crucial for autophagosome–lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation

Members of the Atg8 family of proteins are conjugated to autophagosomal membranes, where they have been proposed to drive autophagosome formation and selective sequestration of cargo. In mammals, the Atg8 family consists of six members divided into the LC3 and GABARAP subfamilies. To define Atg8 fun...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Cell Biol
Main Authors: Nguyen, Thanh Ngoc, Padman, Benjamin Scott, Usher, Joanne, Oorschot, Viola, Ramm, Georg, Lazarou, Michael
פורמט: Artigo
שפה:Inglês
יצא לאור: The Rockefeller University Press 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5166504/
https://ncbi.nlm.nih.gov/pubmed/27864321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201607039
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