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Atg8 family LC3/GABARAP proteins are crucial for autophagosome–lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation

Members of the Atg8 family of proteins are conjugated to autophagosomal membranes, where they have been proposed to drive autophagosome formation and selective sequestration of cargo. In mammals, the Atg8 family consists of six members divided into the LC3 and GABARAP subfamilies. To define Atg8 fun...

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Detaylı Bibliyografya
Yayımlandı:J Cell Biol
Asıl Yazarlar: Nguyen, Thanh Ngoc, Padman, Benjamin Scott, Usher, Joanne, Oorschot, Viola, Ramm, Georg, Lazarou, Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5166504/
https://ncbi.nlm.nih.gov/pubmed/27864321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201607039
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