Defective dendritic cell migration and activation of adaptive immunity in PI3Kγ-deficient mice

Gene-targeted mice were used to evaluate the role of the gamma isoform of phosphoinositide 3-kinase (PI3Kγ) in dendritic cell (DC) migration and induction of specific T-cell-mediated immune responses. DC obtained from PI3Kγ−/− mice showed a reduced ability to respond to chemokines in vitro and ex vi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Del Prete, Annalisa, Vermi, William, Dander, Erica, Otero, Karel, Barberis, Laura, Luini, Walter, Bernasconi, Sergio, Sironi, Marina, Santoro, Amerigo, Garlanda, Cecilia, Facchetti, Fabio, Wymann, Matthias P, Vecchi, Annunciata, Hirsch, Emilio, Mantovani, Alberto, Sozzani, Silvano
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC516633/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15318168/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600361
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados