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The atypical receptor CCRL2 is essential for NK cell-dependent resistance against lung cancer

CCRL2 is a non-signaling seven-transmembrane domain receptor. CCRL2 binds chemerin, a protein that promotes chemotaxis of selected leukocyte subsets including NK cells. In addition, CCRL2 controls the inflammatory response in different pathological settings. Here we investigated the role of CCRL2 in...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Del Prete, Annalisa, Sozio, Francesca, Schioppa, Tiziana, Ponzetta, Andrea, Vermi, William, Calza, Stefano, Bugatti, Mattia, Salvi, Valentina, Bernardini, Giovanni, Benvenuti, Federica, Vecchi, Annunciata, Bottazzi, Barbara, Mantovani, Alberto, Sozzani, Silvano
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176487/
https://ncbi.nlm.nih.gov/pubmed/31484658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-19-0168
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